Manchester United will face off with Spanish opposition Real Betis while Arsenal have been will be against Sporting Lisbon. The Red Devils overcame Barcelona 4-3 to on aggregate in a thrilling playoff round to advance to this stage of the competition while Arsenal topped their group to advance directly to this stage. 

The first leg between Manchester United vs Real Betis will take place at Old Trafford on Thursday 9th March while the second fixture will play out at Benito Villamarin just one week later on March 16th. Sporting Lisbon will host their first-leg match against Arsenal at the Estadio Jose Alvalade before travelling to the Emirates Stadium on the following week.

The other teams that have been drawn together in the round include Union Berlin v Union SG, Shakhtar Donetsk v Feyenoord, Roma v Real Sociedad, Bayern Leverkusen v Ferencvarosi, Sevilla v Fenerbahce, and Juventus v SC Freiburg. There will be no derbies in the draw. 

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